Mesiotemporal changes on magnetic resonance imaging in neurosyphilis
- PMID: 24020346
- DOI: 10.1111/j.1445-5994.2012.02829.x
Mesiotemporal changes on magnetic resonance imaging in neurosyphilis
Abstract
We report a case of neurosyphilis with magnetic resonance imaging (MRI) brain scan findings compatible with a diagnosis of herpes simplex encephalitis with negative testing for herpes simplex virus in the cerebral spinal fluid. An extensive review of the literature has been undertaken revealing 24 cases worldwide where there are mesiotemporal changes on MRI concurrent with a diagnosis of neurosyphilis. Therefore, it is now well established that neurosyphilis, 'the great imitator', should be considered in the differential diagnosis in all patients demonstrating mesiotemporal changes on MRI, changes usually seen in herpes simplex encephalitis.
Keywords: herpes encephalitis; magnetic resonance imaging; mesiotemporal; syphilis.
© 2012 The Authors. Internal Medicine Journal © 2012 Royal Australasian College of Physicians.
Comment in
-
Mesiotemporal neuroimaging abnormalities in neurosyphilis and other causes of limbic encephalitis.Intern Med J. 2013 Apr;43(4):470. doi: 10.1111/imj.12053. Intern Med J. 2013. PMID: 23551320 No abstract available.
-
Author reply to Kleinig.Intern Med J. 2013 Apr;43(4):470-1. doi: 10.1111/imj.12092. Intern Med J. 2013. PMID: 23551321 No abstract available.
-
Cavernous sinus syndrome: a rare complication of neurosyphilis.Intern Med J. 2014 Apr;44(4):428-9. doi: 10.1111/imj.12356. Intern Med J. 2014. PMID: 24754696 No abstract available.
-
Author reply: To PMID 24020346.Intern Med J. 2014 Apr;44(4):429. doi: 10.1111/imj.12388. Intern Med J. 2014. PMID: 24754697 No abstract available.
Similar articles
-
Differential diagnosis of mesiotemporal lesions: case report of neurosyphilis.Neuroradiology. 2005 Sep;47(9):664-7. doi: 10.1007/s00234-005-1414-4. Epub 2005 Jul 15. Neuroradiology. 2005. PMID: 16021441
-
Neuroimaging of six neurosyphilis cases mimicking viral encephalitis.J Neurol Sci. 2013 Nov 15;334(1-2):164-6. doi: 10.1016/j.jns.2013.08.019. Epub 2013 Aug 19. J Neurol Sci. 2013. PMID: 24007871
-
MRI of neurosyphilis presenting as mesiotemporal abnormalities: a case report.Korean J Radiol. 2009 May-Jun;10(3):310-2. doi: 10.3348/kjr.2009.10.3.310. Epub 2009 Apr 22. Korean J Radiol. 2009. PMID: 19412521 Free PMC article.
-
Neurosyphilis with mesiotemporal magnetic resonance imaging abnormalities.Intern Med. 2008;47(20):1813-7. doi: 10.2169/internalmedicine.47.0983. Epub 2008 Oct 15. Intern Med. 2008. PMID: 18854635 Review.
-
Syphilis: reemergence of an old adversary.Ophthalmology. 2006 Nov;113(11):2074-9. doi: 10.1016/j.ophtha.2006.05.048. Epub 2006 Aug 28. Ophthalmology. 2006. PMID: 16935333 Review.
Cited by
-
Clinical and Laboratory Characteristics, Neuroimaging Alternations and Treatment Response of 25 HIV-Negative General Paresis Patients.Infect Drug Resist. 2023 Oct 30;16:6931-6939. doi: 10.2147/IDR.S421672. eCollection 2023. Infect Drug Resist. 2023. PMID: 37928605 Free PMC article.
-
Concomitant neurosyphilis and herpes simplex encephalitis in an immunocompetent patient: a case report.Neurol Sci. 2018 Jan;39(1):185-187. doi: 10.1007/s10072-017-3115-2. Epub 2017 Sep 15. Neurol Sci. 2018. PMID: 28914386 No abstract available.
-
Use of clinical and neuroimaging characteristics to distinguish temporal lobe herpes simplex encephalitis from its mimics.Clin Infect Dis. 2015 May 1;60(9):1377-83. doi: 10.1093/cid/civ051. Epub 2015 Jan 30. Clin Infect Dis. 2015. PMID: 25637586 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
