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Comment
. 2013 Aug 12;26(3):221-2.
doi: 10.1016/j.devcel.2013.07.018.

PREEParing for mitosis

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PREEParing for mitosis

Brian Burke. Dev Cell. .
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Abstract

Reporting in Developmental Cell, Schlaitz et al. (2013) show that endoplasmic reticulum (ER) membrane exclusion from the mitotic spindle is an active process requiring REEP membrane proteins. REEP protein depletion results in ER membrane retention on the spindle and chromosomes, leading to defects in chromosome segregation and nuclear envelope assembly.

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