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Review
. 2013 May;27(5):580-5.

[Application of genipin for modification of natural biomaterials as a crosslinking agent]

[Article in Chinese]
Affiliations
  • PMID: 23879096
Review

[Application of genipin for modification of natural biomaterials as a crosslinking agent]

[Article in Chinese]
Min Wang et al. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2013 May.

Abstract

Objective: To review the application of genipin for the modification of natural biomaterials as a crosslinking agent and progress in research.

Methods: Domestic and foreign literature on application of genipin for the modification of natural biomaterials as a crosslinking agent was thoroughly reviewed. Results Genipin is an effective natural crosslinking agent with a very low level of cytotoxicity compared with conventional synthetic crosslinking agents. Tissues fixed with genipin can maintain a high level of stability as well as resistance to enzymatic degradation.

Conclusion: Genipin is a promising substitute for conventional synthetic crosslinking agents, which has offered an alternative for modification of natural biomaterials for tissue engineering.

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