Burden and health-related quality of life among caregivers of Brazilian Parkinson's disease patients
- PMID: 23831481
- DOI: 10.1016/j.parkreldis.2013.06.005
Burden and health-related quality of life among caregivers of Brazilian Parkinson's disease patients
Abstract
Purpose: To analyze the main determinants of burden and health-related quality-of-life (HRQoL) in caregivers of Brazilian Parkinson's disease (PD) patients.
Methods: Caregivers answered Hospital Anxiety and Depression Scale (HADS), Zarit caregiver burden interview (ZCBI) and EQ-5D, a generic measure of HRQoL. Patients were assessed with Hoehn and Yahr (H&Y) staging; Scales for Outcomes in Parkinson's disease (SCOPA) Motor, Cognition, Psychosocial and Sleep scales; Non-Motor Symptoms Scale; HADS; Clinical Impression of Severity Index; EQ-5D and Parkinson's Psychosis Rating Scale.
Results: 50 Caregiver-patient dyads were assessed. Caregivers were significantly younger (55.7 vs. 65.4 years), p < 0.0001. Eighty-eight per cent of caregivers were females, and 78% were spouses. The proportion of caregivers who scored ≥11 points in the HADS-anxiety or HADS-depression subscales was 12% and 14% respectively. ZCBI mean score was 20.2 (SD 12.8), and significantly worsened as severity of disease, based on H&Y, increased (H&Y 1-2: 16.4, H&Y 3-5: 24.6; p = 0.02). Caregiver's EQ-5D Index and visual analog scale mean scores were 0.7 (SD: 0.26) and 76.3 (SD: 16.2) respectively. Weak to moderate association (r = -0.27 to -0.39) between EQ-5D Index and ZBCI mean scores was observed in caregivers. Patient outcomes (sleep disorders and behavioral-psychotic symptoms) and caregiver outcomes (mood, time of caregiving) were independent predictors of caregiver burden (adjusted R(2) = 0.55; p < 0.0001) in the multivariate regression analysis. Caregiver's mood status was a significant determinant of caregiver's HRQoL, as measured by the EQ-5D Index (adjusted R(2) = 0.28; p = 0.006).
Conclusions: Patients' psychiatric and sleep disorders and caregiver's mood significantly influenced burden and HRQoL in Brazilian PD caregivers.
Keywords: Burden; Caregivers; Depression; Health status; Parkinson's disease; Quality of life.
Copyright © 2013 Elsevier Ltd. All rights reserved.
Similar articles
-
Burden and perceived health status among caregivers of stroke patients.Cerebrovasc Dis. 2009;28(5):472-80. doi: 10.1159/000236525. Epub 2009 Sep 10. Cerebrovasc Dis. 2009. PMID: 19752548
-
Burden, perceived health status, and mood among caregivers of Parkinson's disease patients.Mov Disord. 2008 Sep 15;23(12):1673-80. doi: 10.1002/mds.22106. Mov Disord. 2008. PMID: 18709684
-
Caregiver burden in Parkinson's disease.Mov Disord. 2007 May 15;22(7):924-31; quiz 1060. doi: 10.1002/mds.21355. Mov Disord. 2007. PMID: 17238193
-
[Caregiver burden in relatives of persons with schizophrenia: an overview of measure instruments].Encephale. 2003 Mar-Apr;29(2):137-47. Encephale. 2003. PMID: 14567165 Review. French.
-
Health-related quality of life in Parkinson's disease: systematic review and meta-analysis of EuroQol (EQ-5D) utility scores.Qual Life Res. 2024 Jul;33(7):1781-1793. doi: 10.1007/s11136-024-03646-8. Epub 2024 Apr 6. Qual Life Res. 2024. PMID: 38581635 Review.
Cited by
-
Insomnia in Parkinson's Disease: Causes, Consequences, and Therapeutic Approaches.Mol Neurobiol. 2024 Aug 5. doi: 10.1007/s12035-024-04400-4. Online ahead of print. Mol Neurobiol. 2024. PMID: 39103716 Review.
-
The Interrelationship of Benefit Finding, Demoralization, and Stigma among Patients with Parkinson's Disease and Their Caregivers.Healthcare (Basel). 2024 Apr 23;12(9):878. doi: 10.3390/healthcare12090878. Healthcare (Basel). 2024. PMID: 38727435 Free PMC article.
-
Patient With Parkinson Disease and Care Partner Perceptions of Key Domains Affecting Health-Related Quality of Life: Systematic Review.Neurology. 2024 Feb 13;102(3):e208028. doi: 10.1212/WNL.0000000000208028. Epub 2024 Jan 12. Neurology. 2024. PMID: 38215353 Free PMC article.
-
Contributory Factors to Caregiver Burden in Parkinson's Disease.Mov Disord Clin Pract. 2023 Aug 30;10(10):1507-1518. doi: 10.1002/mdc3.13868. eCollection 2023 Oct. Mov Disord Clin Pract. 2023. PMID: 37868922 Free PMC article.
-
Predictors of Burden in Carers of Patients with Impulse Control Behaviors in Parkinson's Disease.Mov Disord Clin Pract. 2023 Jul 26;10(9):1360-1367. doi: 10.1002/mdc3.13824. eCollection 2023 Sep. Mov Disord Clin Pract. 2023. PMID: 37772283 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical