Abstract

Keywords: AD; ADAM10; ALS; AP1; APOE; APP; ASC; ATG; Ageing; Alzheimer's disease; Ambra1; AuTophaGy-related; Autophagy; B-cell lymphoma 2; B-cell lymphoma-extra large; BACE1; BAD; BAK; BAR; BAX; BCL2/adenovirus E1B 19kDa protein-interacting protein 3; BECN; BH3; BH3-only protein; BNIP3; BNIP3-like; Bax-interacting factor-1; Bcl-2; Bcl-2 antagonist killer; Bcl-2 interacting protein 1; Bcl-2-associated X protein; Bcl-2-associated death promoter; Bcl-2-homology-3 domain; Bcl-2-interacting protein; Bcl-xL; Beclin 1; Beclin 1 gene; Bif-1; Bim; Bin-Amphiphysin-Rvs domain; CARD9, BCL10, and MALT1 complex; CBM; CCD; CD46; CD46 antigen; CDK; CLU; Casp1; DAPK; DR; Drp1; ECD; EGF; ER; FK506 binding protein 38; FKBP38; FYVE finger-containing phosphoinositide kinase; Fis1; Forkhead box O; FoxO; GGA; GOPC; GSK3β; Golgi-associated PD2 and coiled-coil domains-containing protein; Golgi-associated PDZ and coiled-coil domains-containing protein; Golgi-associated, γ-adaptin ear-containing, ARF-binding protein; HIV; HMGB1; HSV; Hsp; ICP34.5; IFN; IL; IP3; JNK; LAMP2a; LC3; MCI; MIG-14; Mfn; Mitophagy; Myd88; N-methyl-D-aspartate; NACHT; NADPH oxidase 2; NF-κB; NIX; NLRP; NMDA; NO; NOD-like receptor family, pyrin domain containing; NOX2; Nef; Noxa; Nrf2; Opa1; PD; PERK; PI(3)P; PIKfyve; PINK1; PKD; PS; PSEN; PTEN-induced putative kinase 1; Parkin; Parkinson's disease; Phox; Pik3C3; Puma; RAS-related GTP-binding protein 7; RING-domain-containing E3 ubiquitin ligase; RIP1; ROS; RTN3; Rab7; SNARE; SNX; Slam family member 1; Slamf1; SorLA; Sortilin-related receptor; TAB; TAK1; TAK1 binding protein; TG2; TGFβ; TGFβ-activated kinase 1; TGN; TIR domain-containing adaptor inducing IFNβ; TLR; TNF receptor associated factor 6; TNF-related apoptosis-inducing ligand; TNF-α; TPC; TRAF6; TRAIL; TRIF; TRS1; Toll-like receptor; Tomm40; UBA; ULK1; UVRAG; Vps; Vps34; WD repeat domain phosphoinositide-interacting protein 1; WIPI-1; a disintegrin and metalloproteinase domain 10; activating molecule in Beclin 1-regulated autophagy; amyloid-β precursor protein; amyotrophic lateral sclerosis; apolipoprotein E gene; apoptosis-associated speck-like protein; c-Jun N-terminal kinase; caspase-1; clathrin adaptor-related protein; clusterin gene; coiled-coil domain; cyclin-dependent kinase; cytomegalovirus protein; death receptor; death-associated protein kinase; dynamin-related protein 1; endoplasmic reticulum; epidermal growth factor; eukaryotic translation initiation factor 2α kinase 3; evolutionarily conserved domain; glycogen synthase kinase 3β; heat shock protein; herpex simplex virus; high-mobility group protein B1; human immunodeficiency virus; infected cell protein 34.5; inositol 1,4,5-trisphosphate; interferon; interleukin; lysosome-associated membrane protein 2a; miR; microRNAs; microtubule-associated protein 1 light chain 3; mild cognitive impairment; mitochondrial fission 1 protein; mitofusin; myeloid differentiation primary response gene 88; nPIST; negative regulatory factor; neuronal isoform of protein-interacting specifically with TC10; nitric oxide; nuclear factor erythroid 2-like 2; nuclear factor-κB; nucleotide-binding and oligomerization domain; optic atrophy 1; phosphatidylinositol 3-kinase; phosphatidylinositol 3-phosphate; phosphoinositide-binding domain; presenilin; presenilin gene; protein kinase D; reactive oxygen species; receptor-interacting protein 1; reticulon 3; retromer cargo protein in C. elegans; soluble NSF attachment protein receptor; sorting nexin; trans-Golgi network; transforming growth factor β; transglutaminase 2; translocase of outer mitochondrial membrane 40 homolog; tumor necrosis factor-α; two pore segment channel 1; ubiquitin-associated domain; ultraviolet irradiation resistance-associated gene; unc-51-like kinase 1; vesicular protein-sorting protein; β-site amyloid-β A4 precursor protein-cleaving enzyme 1.