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Review
. 2013 Jun;34(2):273-82.
doi: 10.1016/j.ccm.2013.02.002. Epub 2013 Apr 8.

Human immunodeficiency virus-associated obstructive lung diseases

Matthew R Gingo  1 , Alison Morris, Kristina Crothers
Affiliations
Review

Human immunodeficiency virus-associated obstructive lung diseases

Matthew R Gingo et al. Clin Chest Med. 2013 Jun.

Abstract

In the era of effective antiretroviral therapy (ART), epidemiologic studies have found that persons infected with human immunodeficiency virus (HIV) have a higher prevalence and incidence of chronic obstructive pulmonary disease than HIV-uninfected persons. In comparison with HIV-uninfected persons and those with well-controlled HIV disease, HIV-infected persons with poor viral control or lower CD4 cell count have more airflow obstruction, a greater decline in lung function, and possibly more severe diffusing impairment. This article reviews the evidence linking HIV infection to obstructive lung disease, and discusses management issues related to the treatment of obstructive lung disease in HIV-infected patients.

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Figures

Figure 1
Figure 1
Mechanisms related to obstructive lung disease in HIV-infected persons grouped by association with COPD/emphysema and association with asthma/airway hyperreactivity.
See this image and copyright information in PMC

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