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. 2011;1(4):203-11.
doi: 10.5681/bi.2011.029. Epub 2011 Nov 9.

Antiviral activity of natural products extracted from marine organisms

Bushra Uzair  1 , Zahra Mahmood, Sobia Tabassum
Affiliations

Antiviral activity of natural products extracted from marine organisms

Bushra Uzair et al. Bioimpacts. 2011.

Abstract

Many epidemics have broken out over the centuries. Hundreds and thousands of humans have died over a disease. Available treatments for infectious diseases have always been limited. Some infections are more deadly than the others, especially viral pathogens. These pathogens have continuously resisted all kinds of medical treatment, due to a need for new treatments to be developed. Drugs are present in nature and are also synthesized in vitro and they help in combating diseases and restoring health. Synthesizing drugs is a hard and time consuming task, which requires a lot of man power and financial aid. However, the natural compounds are just lying around on the earth, may it be land or water. Over a thousand novel compounds isolated from marine organisms are used as antiviral agents. Others are being pharmacologically tested. Today, over forty antiviral compounds are present in the pharmacological market. Some of these compounds are undergoing clinical and preclinical stages. Marine compounds are paving the way for a new trend in modern medicine.

Keywords: Antiviral Compounds; HIV; Marine Life-Forms; Pharmacology.

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References

    1. Ahmad AS, Matsuda M, Shigeta S and Okutani K . 1999 Revelation of antiviral activities by artificial sulfation of a glycosaminoglycan from a marine Pseudomonas Mar . Biotechnol, 1, 102-106 - PubMed
    1. Amornrut C, Toida T, Imanari T, Woo ER, Park H, Linhardt R, et al.1999 A new sulfated beta-galactan from clams with anti-HIV activity. Carbohydrate Res, 321, 121-127 - PubMed
    1. Artan M, Li Y, Karadeniz F, Lee SH, Kim MM, Kim SK, et al.2008 Anti-HIV-1 activity of phloroglucinol derivative, 6, 6′-bieckol, from Ecklonia cava. Bioorg. Med. Chem, 16, 7921-7926 - PubMed
    1. Bergman W and Feeney RJ . 1951 Nucleosides of sponges. J. Org. Chem, 16, 981-987
    1. Chang L, Whittaker NF and Bewley CA . 2003 Crambescidin 826 and dehydrocrambine A: new polycyclic guanidine alkaloids from the marine sponge Monanchora sp . that inhibit HIV-1 fusion. J. Nat. Prod, 66, 1490-1494 - PubMed

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