Enantiomeric differentiation by synthetic helical polymers
- PMID: 23666081
- DOI: 10.1007/128_2013_439
Enantiomeric differentiation by synthetic helical polymers
Abstract
Recent advances in the synthesis of helical polymers and their applications as chiral materials, in particular chiral stationary phases (CSPs), for high-performance liquid chromatography (HPLC) are reviewed with an emphasis on the key role of the helical conformations with one-handedness for the prominent chiral recognition of enantiomers. The historical background of artificial optically active helical polymers is also briefly described.
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