Schizophrenia at a genetics crossroads: where to now?

doi:10.1093/schbul/sbt041

. 2013 May;39(3):490-5.

doi: 10.1093/schbul/sbt041. Epub 2013 Mar 21.

Schizophrenia at a genetics crossroads: where to now?

Aiden Corvin¹

Affiliations

Affiliation

¹ Department of Psychiatry & Neuropsychiatric Genetics Research Group, Institute of Molecular Medicine, Trinity College Dublin, Dublin 2, Ireland. acorvin@tcd.ie

PMID: 23519022
PMCID: PMC3627765
DOI: 10.1093/schbul/sbt041

Schizophrenia at a genetics crossroads: where to now?

Aiden Corvin. Schizophr Bull. 2013 May.

. 2013 May;39(3):490-5.

doi: 10.1093/schbul/sbt041. Epub 2013 Mar 21.

Author

Aiden Corvin¹

Affiliation

¹ Department of Psychiatry & Neuropsychiatric Genetics Research Group, Institute of Molecular Medicine, Trinity College Dublin, Dublin 2, Ireland. acorvin@tcd.ie

PMID: 23519022
PMCID: PMC3627765
DOI: 10.1093/schbul/sbt041

No abstract available

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Figures

**Fig. 1.**
A model of the schizophrenia network demonstrating subnetworks, network hubs and nodes, and potential for overlaps with other disorders.

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Unlocking the treasure trove: from genes to schizophrenia biology.
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Association of common variants in H2AFZ gene with schizophrenia and cognitive function in patients with schizophrenia.
Chang M, Sun L, Liu X, Sun W, You X. Chang M, et al. J Hum Genet. 2015 Oct;60(10):619-24. doi: 10.1038/jhg.2015.89. Epub 2015 Aug 6. J Hum Genet. 2015. PMID: 26246156 Clinical Trial.
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Where GWAS and epidemiology meet: opportunities for the simultaneous study of genetic and environmental risk factors in schizophrenia.
McGrath JJ, Mortensen PB, Visscher PM, Wray NR. McGrath JJ, et al. Schizophr Bull. 2013 Sep;39(5):955-9. doi: 10.1093/schbul/sbt108. Epub 2013 Aug 1. Schizophr Bull. 2013. PMID: 23907349 Free PMC article. Review. No abstract available.

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References

1. Sullivan PF. The psychiatric GWAS consortium: big science comes to psychiatry. Neuron. 2010; 68: 182–186 - PMC - PubMed
1. Owen MJ. Implications of genetic findings for understanding schizophrenia. Schizophr Bull. 2012; 38: 904–907 - PMC - PubMed
1. Sullivan PF, Daly MJ, O’Donovan M. Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nat Rev Genet. 2012; 13: 537–551 - PMC - PubMed
1. Malhotra D, Sebat J. CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell. 2012; 148: 1223–1241 - PMC - PubMed
1. Ripke S. XXth World Congress of Psychiatric Genetics; 14-18 October 2012; Hamburg, Germany.

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[1] Sullivan PF. The psychiatric GWAS consortium: big science comes to psychiatry. Neuron. 2010; 68: 182–186 - PMC - PubMed

[2] Sullivan PF. The psychiatric GWAS consortium: big science comes to psychiatry. Neuron. 2010; 68: 182–186 - PMC - PubMed

[3] Owen MJ. Implications of genetic findings for understanding schizophrenia. Schizophr Bull. 2012; 38: 904–907 - PMC - PubMed

[4] Owen MJ. Implications of genetic findings for understanding schizophrenia. Schizophr Bull. 2012; 38: 904–907 - PMC - PubMed

[5] Sullivan PF, Daly MJ, O’Donovan M. Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nat Rev Genet. 2012; 13: 537–551 - PMC - PubMed

[6] Sullivan PF, Daly MJ, O’Donovan M. Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nat Rev Genet. 2012; 13: 537–551 - PMC - PubMed

[7] Malhotra D, Sebat J. CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell. 2012; 148: 1223–1241 - PMC - PubMed

[8] Malhotra D, Sebat J. CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell. 2012; 148: 1223–1241 - PMC - PubMed

[9] Ripke S. XXth World Congress of Psychiatric Genetics; 14-18 October 2012; Hamburg, Germany.

[10] Ripke S. XXth World Congress of Psychiatric Genetics; 14-18 October 2012; Hamburg, Germany.

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Schizophrenia at a genetics crossroads: where to now?

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Schizophrenia at a genetics crossroads: where to now?

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