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Review
. 2013 Mar;252(1):133-8.
doi: 10.1111/imr.12034.

Th1- and Th2-like subsets of innate lymphoid cells

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Review

Th1- and Th2-like subsets of innate lymphoid cells

Jochem Bernink et al. Immunol Rev. 2013 Mar.

Abstract

Innate lymphoid cells (ILCs) constitute a family of effectors in innate immunity and regulators of tissue remodeling that have a cytokine and transcription factor expression pattern that parallels that of the T-helper (Th) cell family. Here, we discuss how ILCs can be categorized and summarize the current knowledge of Th1- and Th2-like ILCs with regard to the molecular mechanisms of development, effector functions, and their interplay with other cell types.

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