Th1- and Th2-like subsets of innate lymphoid cells
- PMID: 23405900
- DOI: 10.1111/imr.12034
Th1- and Th2-like subsets of innate lymphoid cells
Abstract
Innate lymphoid cells (ILCs) constitute a family of effectors in innate immunity and regulators of tissue remodeling that have a cytokine and transcription factor expression pattern that parallels that of the T-helper (Th) cell family. Here, we discuss how ILCs can be categorized and summarize the current knowledge of Th1- and Th2-like ILCs with regard to the molecular mechanisms of development, effector functions, and their interplay with other cell types.
© 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.
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