Subcutaneous gold nanorods [corrected] detection with diffusion reflection measurement
- PMID: 23389735
- DOI: 10.1117/1.JBO.18.6.061226
Subcutaneous gold nanorods [corrected] detection with diffusion reflection measurement
Erratum in
- J Biomed Opt. 2013 Jul;18(7):079801
Abstract
The ability to quantitatively and noninvasively detect nanoparticles nearby the skin surface has important implications on their development as an in vivo cancer diagnostic tool. The diffusion reflection (DR) method is a simple, noninvasive imaging technique which has been proven useful for the investigation of the optical parameters of the tissue. A new method is presented for the measurements of gold nanorod (GNR) concentration in tissue-like phantoms, based on DR measurement and intense light absorption of GNR. Monte Carlo simulations and tissue-like phantom measurements of the reflected light intensity are presented. The ability to extract optical properties of phantoms and their GNR concentrations from DR measurements is demonstrated, followed by a discussion about the best mathematical model for light propagation in tissues, based on the diffusion theory.
Similar articles
-
In-vivo Tumor detection using diffusion reflection measurements of targeted gold nanorods - a quantitative study.J Biophotonics. 2012 Mar;5(3):263-73. doi: 10.1002/jbio.201100120. Epub 2012 Jan 11. J Biophotonics. 2012. PMID: 22234916
-
A new method for cancer detection based on diffusion reflection measurements of targeted gold nanorods.Int J Nanomedicine. 2012;7:449-55. doi: 10.2147/IJN.S28424. Epub 2012 Jan 31. Int J Nanomedicine. 2012. PMID: 22334777 Free PMC article.
-
Gold nanorods as absorption contrast agents for the noninvasive detection of arterial vascular disorders based on diffusion reflection measurements.Nano Lett. 2014 May 14;14(5):2681-7. doi: 10.1021/nl500573d. Epub 2014 Apr 8. Nano Lett. 2014. PMID: 24697682
-
Gold nanorods as molecular contrast agents in photoacoustic imaging: the promises and the caveats.Contrast Media Mol Imaging. 2011 Sep-Oct;6(5):389-400. doi: 10.1002/cmmi.454. Contrast Media Mol Imaging. 2011. PMID: 22025339 Review.
-
Nanotechnology: a promising method for oral cancer detection and diagnosis.J Nanobiotechnology. 2018 Jun 11;16(1):52. doi: 10.1186/s12951-018-0378-6. J Nanobiotechnology. 2018. PMID: 29890977 Free PMC article. Review.
Cited by
-
Detecting nanoparticles in tissue using an optical iterative technique.Biomed Opt Express. 2014 Oct 10;5(11):3871-81. doi: 10.1364/BOE.5.003871. eCollection 2014 Nov 1. Biomed Opt Express. 2014. PMID: 25426317 Free PMC article.
-
Diffusion Reflection and Fluorescence Lifetime Imaging Microscopy Study of Fluorophore-Conjugated Gold Nanoparticles or Nanorods in Solid Phantoms.ACS Photonics. 2014 Sep 17;1(9):900-905. doi: 10.1021/ph500214m. Epub 2014 Aug 25. ACS Photonics. 2014. PMID: 25541621 Free PMC article.
-
Detection of gold nanorods uptake by macrophages using scattering analyses combined with diffusion reflection measurements as a potential tool for in vivo atherosclerosis tracking.Int J Nanomedicine. 2015 Jul 9;10:4437-46. doi: 10.2147/IJN.S86615. eCollection 2015. Int J Nanomedicine. 2015. PMID: 26185445 Free PMC article.
-
An ultra-sensitive dual-mode imaging system using metal-enhanced fluorescence in solid phantoms.Nano Res. 2015 Dec 1;8(12):3912-3921. doi: 10.1007/s12274-015-0891-y. Nano Res. 2015. PMID: 26870306 Free PMC article.
-
Nanoparticle-free tissue-mimicking phantoms with intrinsic scattering.Biomed Opt Express. 2016 May 4;7(6):2088-94. doi: 10.1364/BOE.7.002088. eCollection 2016 Jun 1. Biomed Opt Express. 2016. PMID: 27375928 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical