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. 2013 Jan;41(Database issue):D30-5.
doi: 10.1093/nar/gks1175. Epub 2012 Nov 29.

Facing growth in the European Nucleotide Archive

Guy Cochrane  1 , Blaise Alako, Clara Amid, Lawrence Bower, Ana Cerdeño-Tárraga, Iain Cleland, Richard Gibson, Neil Goodgame, Mikyung Jang, Simon Kay, Rasko Leinonen, Xiu Lin, Rodrigo Lopez, Hamish McWilliam, Arnaud Oisel, Nima Pakseresht, Swapna Pallreddy, Youngmi Park, Sheila Plaister, Rajesh Radhakrishnan, Stephane Rivière, Marc Rossello, Alexander Senf, Nicole Silvester, Dmitriy Smirnov, Petra Ten Hoopen, Ana Toribio, Daniel Vaughan, Vadim Zalunin
Affiliations

Facing growth in the European Nucleotide Archive

Guy Cochrane et al. Nucleic Acids Res. 2013 Jan.

Abstract

The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena/) collects, maintains and presents comprehensive nucleic acid sequence and related information as part of the permanent public scientific record. Here, we provide brief updates on ENA content developments and major service enhancements in 2012 and describe in more detail two important areas of development and policy that are driven by ongoing growth in sequencing technologies. First, we describe the ENA data warehouse, a resource for which we provide a programmatic entry point to integrated content across the breadth of ENA. Second, we detail our plans for the deployment of CRAM data compression technology in ENA.

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Figures

Figure 1.
Figure 1.
Accumulation of raw data into ENA. The figure shows the accumulation of raw next generation sequence data into public data repositories. In addition to unrestricted data available in ENA, the figure also shows the accumulation of sequence data into the European Bioinformatics Institute's, European Genome-phenome Archive, a repository for human molecular medicine research-related data requiring authorized access for ethical reasons (http://www.ebi.ac.uk/ega/). Data points for expected output of global cancer genome sequencing projects are shown.
Figure 2.
Figure 2.
Query builder interface screenshot. The figure shows the query builder graphical user interface for the ENA warehouse search service. This interface is available from the ‘Advanced search’ tab visible across the ENA browser.
See this image and copyright information in PMC

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