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Review
. 2013 Feb;27(2):199-207.
doi: 10.1038/eye.2012.243. Epub 2012 Nov 30.

Oculoplastic aspects of ocular oncology

Affiliations
Review

Oculoplastic aspects of ocular oncology

C Rene. Eye (Lond). 2013 Feb.

Abstract

It is estimated that 5-10% of all cutaneous malignancies involve the periocular region and management of periocular skin cancers account for a significant proportion of the oculoplastic surgeon's workload. Epithelial tumours are most frequently encountered, including basal cell carcinoma, squamous cell carcinoma, and sebaceous gland carcinoma, in decreasing order of frequency. Non-epithelial tumours, such as cutaneous melanoma and Merkel cell carcinoma, rarely involve the ocular adnexae. Although non-surgical treatments for periocular malignancies are gaining in popularity, surgery remains the main treatment modality and has as its main aims tumour clearance, restoration of the eyelid function, protection of the ocular surface, and achieving a good cosmetic outcome. The purpose of this article is to review the management of malignant periocular tumours, with particular emphasis on surgical management.

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Figures

Figure 1
Figure 1
Morphological varieties of BCC. (a) Nodular, (b) noduloulcerative, (c) cystic, (d) extensive morpheaform BCC with ulceration and orbital invasion, and (e) pigmented BCC in lash line with adjacent pigmented intradermal naevus on lid margin.
Figure 2
Figure 2
SCC. (a) This ulcerating SCC at right medial canthus could be confused for a BCC because of the rolled edge. (b) A fleshy mass causing mechanical left lower lid ectropion and invading the orbit. (c) A large neglected SCC on the right upper lid causing mechanical ptosis. Note the hyperkeratosis on the surface.
Figure 3
Figure 3
SGC of the left upper lid masquerading as an atypical chalazion.
Figure 4
Figure 4
SCC left upper lid with lacrimal gland involvement many years after radiotherapy for cutaneous T-cell lymphoma. Note the cutaneous changes because of radiation dermatitis.
Figure 5
Figure 5
Pre-operative, per-operative, and post-operative appearance of a large ulcerating BCC on the upper lid. The resultant defect was repaired with a supraclavicular skin graft.

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