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Review
. 2012:104:47-70.
doi: 10.1016/B978-0-12-398323-7.00003-3.

Accessing and mining data from large-scale mouse phenotyping projects

Hugh Morgan  1 , Michelle Simon, Ann-Marie Mallon
Affiliations
Review

Accessing and mining data from large-scale mouse phenotyping projects

Hugh Morgan et al. Int Rev Neurobiol. 2012.

Abstract

Comprehensive phenotyping through the International Mouse Phenotyping Consortium (IMPC)-www.mousephenotype.org-will reveal the pleiotropic functions of every gene in the mouse genome and uncover the wider role of genetic loci within diverse biological systems. The informatics challenge will be to develop an infrastructure to acquire the diverse and complex data sets generated from broad-based phenotyping and disseminate these data in an integrated manner to the scientific community. We describe here the current methodologies implemented to capture and disseminate these data, and plans within the Knockout Mouse Phenotyping Project (KOMP2) (http://commonfund.nih.gov/KOMP2/)-funded informatics consortium to scale these implementations to manage the surge in data from the IMPC.

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