Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2012 Oct:30 Suppl 4:25-31.
doi: 10.1016/S0213-005X(12)70101-5.

Circulation of other respiratory viruses and viral co-infection during the 2009 pandemic influenza

José María Navarro-Marí  1 , Mercedes Pérez-Ruiz, Juan Carlos Galán Montemayor, María Ángeles Marcos Maeso, Jordi Reina, María de Oña Navarro, Carlos Gustavo Cilla Eguiluz
Affiliations
Review

Circulation of other respiratory viruses and viral co-infection during the 2009 pandemic influenza

José María Navarro-Marí et al. Enferm Infecc Microbiol Clin. 2012 Oct.

Abstract
in English, Spanish

Coinciding with the pandemic wave of the influenza A(H1N1)pdm09 virus, other respiratory viruses have co-circulated in our area and were responsible for many acute respiratory infections and influenza-like illness (ILI). Apart from the pandemic virus that was responsible for most ILI cases, incidence rates of other viruses have varied among geographical areas. In general, human rhinovirus was the most frequent among individuals from the community, and respiratory syncytial virus among hospitalized patients. Detection rates of other respiratory viruses such as human metapneumovirus, adenovirus or parainfluenza viruses have been much lower. On the basis of an interference mechanism, human rhinovirus may contribute to modulate the pandemic wave, although available data are not conclusive to support this hypothesis. In contrast, the epidemic wave of respiratory syncytial virus during 2009-2010 was similar to previous seasons. Overall, incidence rates of respiratory viruses other than influenza did not change significantly during the pandemic season compared to other seasons. No association has been found between coinfection of pandemic influenza and other respiratory viruses with the prognosis of patients with influenza. The involvement of clinical virology laboratories in the etiological diagnosis of ILI cases has improved and has optimized diagnostic procedures.

Coincidiendo con la onda pandémica 2009 por el virus de la gripe A(H1N1)pdm09, otros virus respiratorios han circulado en nuestro medio, provocando numerosos casos de infección respiratoria aguda y de síndrome gripal (ILI, influenza-like illness). Aparte del virus pandémico, que fue responsable de la mayoría de los casos de ILI, la incidencia de otros virus ha sido diferente según la zona. En general, rinovirus fue el virus más frecuente en la comunidad y virus respiratorio sincitial en pacientes hospitalizados. Las tasas de detección de otros virus como metaneumovirus humano, adenovirus o virus parainfluenza han sido mucho menores. Sobre la base de un mecanismo de interferencia, la presencia de rinovirus pudo contribuir a modular la onda pandémica de gripe, aunque los datos existentes no apoyan esta hipótesis de modo concluyente, mientras que la onda de virus respiratorio sincitial en 2009–2010 se ha presentado de forma similar a otros años. En conjunto, la incidencia de los distintos virus respiratorios de gripe no varió significativamente durante la temporada de la pandemia con respecto a otros años. Por otro lado, no se ha asociado la coinfección por virus de la gripe con otros virus respiratorios con el pronóstico de los pacientes con gripe. La implicación de los laboratorios de virología clínica en el diagnóstico de ILI ha supuesto una mejora y una mayor optimización en los procedimientos diagnósticos.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Zuccotti G., Dilillo D., Zappa A., Galli E., Amendola A., Martinelli M. Epidemiological and clinical features of respiratory viral infections in hospitalized children during the circulation of influenza virus A(H1N1) 2009. Influenza Other Respi Viruses. 2011;5:e528–e534. - PMC - PubMed
    1. Reina J., Riera E., Déniz C. Análisis de la etiología de las infecciones respiratorias víricas en el año de la pandemia de gripe A(H1N1) 2009. Rev Esp Pediatr. 2012;68:183–185.
    1. Chan P.A. Distinguishing characteristics between pandemic 2009–2010 influenza A (H1N1) and other viruses in patients hospitalized with respiratory illness. PloS One. 2011;6:e24734. - PMC - PubMed
    1. Raboni S.M., Stella V., Cruz C.R., França J.B., Moreira S., Gonçalves L. Laboratory diagnosis, epidemiology, and clinical outcomes of pandemic influenza A and community respiratory viral infections in Southern Brazil. J Clin Microbiol. 2011;49:1287–1293. - PMC - PubMed
    1. Lovato-Salas F., Matienzo-Serment L., Monjarás-Avila C., Godoy-Lozano E.E., Comas-Garcia A., Aguilera-Barragán M. Pandemic influenza A (H1N1) 2009 and respiratory syncytial virus associated hospitalizations. J Infect. 2010;61:382–390. - PubMed