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. 2012:2012:531646.
doi: 10.1155/2012/531646. Epub 2012 Sep 26.

Efficacy of music therapy in treatment for the patients with Alzheimer's disease

H Fukui  1 , A Arai, K Toyoshima
Affiliations

Efficacy of music therapy in treatment for the patients with Alzheimer's disease

H Fukui et al. Int J Alzheimers Dis. 2012.

Abstract

We report that music therapy is effective in the treatment of Alzheimer's disease. We found that the secretion of 17β-estradiol and testosterone, hormones that are supposed to have preventive effects on Alzheimer's disease, is significantly increased by music therapy. During the sessions, patients with Alzheimer's disease were allowed to listen to music and songs with verbal contact from the therapist. It was found that problematic behaviors such as poriomania (fugue) had decreased. Music therapy has the potential as an alternative treatment for adverse hormone replacement therapy.

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Figures

Figure 1
Figure 1
Changes in 17 β-estradiol concentrations. Changes in 17 β-estradiol concentrations in 6 patients with Alzheimer's disease at each experimental condition. Two-way ANOVA revealed that the main effect of group (P = 0.0389), main effect of changes in 17 β-estradiol level (P = 0.0026), and interaction with group (P = 0.0177) were significant.
Figure 2
Figure 2
Changes in testosterone concentrations. Changes in testosterone concentrations in 6 patients with Alzheimer's disease at each experimental condition. Two-way ANOVA revealed that the main effect of group (P = 0.05), main effect of changes in testosterone level (P = 0.0066), and interaction with group (P = 0.0063) were significant.
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References

    1. Daniel JM. Estrogens, estrogen receptors, and female cognitive aging: the impact of timing. Hormones and Behavior. In press. - PubMed
    1. Sternbach H. Age-associated testosterone decline in men: clinical issues for psychiatry. American Journal of Psychiatry. 1998;155(10):1310–1318. - PubMed
    1. Lamberts SWJ, Van Den Beld AW, Van Der Lely AJ. The endocrinology of aging. Science. 1997;278(5337):419–424. - PubMed
    1. Holland J, Bandelow S, Hogervorst E. Testosterone levels and cognition in elderly men: a review. Maturitas. 2011;69(4):322–327. - PubMed
    1. Rako S. Testosterone deficiency: a key factor in the increased cardiovascular risk to women following hysterectomy or with natural aging? Journal of Women’s Health. 1998;7(7):825–829. - PubMed

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