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. 2013 Feb;175(1-2):69-74.
doi: 10.1007/s11046-012-9587-y. Epub 2012 Oct 4.

Molecular epidemiology of Malassezia globosa and Malassezia restricta in Sudanese patients with pityriasis versicolor

M Saad  1 , T Sugita, H Saeed, A Ahmed
Affiliations

Molecular epidemiology of Malassezia globosa and Malassezia restricta in Sudanese patients with pityriasis versicolor

M Saad et al. Mycopathologia. 2013 Feb.

Abstract

Pityriasis versicolor is a superficial infection of the stratum corneum caused by Malassezia yeasts. The cutaneous Malassezia globosa and Malassezia restricta in Sudanese patients with pityriasis versicolor were elucidated using a molecular-based, culture-independent method and compared with that in healthy individuals. Scale samples were collected by applying an Opsite™ transparent dressing to lesional and non-lesional sites on 29 Sudanese patients with pityriasis versicolor and 54 healthy individuals. Malassezia DNA was extracted directly from the samples. The overall level of colonization by Malassezia globosa and Malassezia restricta was analyzed by real-time PCR using a TaqMan probe. The overall level of colonization by Malassezia at the lesional sites was higher than that at the non-lesional sites for all body sites, including the face, neck, cheeks, and trunk (2.7- to 6.0-fold increase). Both M. globosa and M. restricta were detected in patients and healthy individuals. However, M. globosa predominated at lesional sites, whereas the level of colonization by both species was similar in healthy individuals.

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References

    1. J Invest Dermatol. 2008 Feb;128(2):345-51 - PubMed
    1. An Bras Dermatol. 2011 Jul-Aug;86(4):803-6 - PubMed
    1. Mycopathologia. 2006 Feb;161(2):61-5 - PubMed
    1. J Dermatol. 2007 Sep;34(9):619-24 - PubMed
    1. Indian J Dermatol Venereol Leprol. 2010 Mar-Apr;76(2):159-64 - PubMed

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