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Randomized Controlled Trial
. 2012 Aug 6:11:55.
doi: 10.1186/1475-2891-11-55.

The effects of four hypocaloric diets containing different levels of sucrose or high fructose corn syrup on weight loss and related parameters

Joshua Lowndes  1 , Diana Kawiecki, Sabrina Pardo, Von Nguyen, Kathleen J Melanson, Zhiping Yu, James M Rippe
Affiliations
Randomized Controlled Trial

The effects of four hypocaloric diets containing different levels of sucrose or high fructose corn syrup on weight loss and related parameters

Joshua Lowndes et al. Nutr J. .

Abstract

Background: The replacement of sucrose with HFCS in food products has been suggested as playing a role in the development of obesity as a public health issue. The objective of this study was to examine the effects of four equally hypocaloric diets containing different levels of sucrose or high fructose corn syrup (HFCS).

Methods: This was a randomized, prospective, double blind trial, with overweight/obese participants measured for body composition and blood chemistry before and after the completion of 12 weeks following a hypocaloric diet. The average caloric deficit achieved on the hypocaloric diets was 309 kcal.

Results: Reductions were observed in all measures of adiposity including body mass, BMI,% body fat, waist circumference and fat mass for all four hypocaloric groups, as well as reductions in the exercise only group for body mass, BMI and waist circumference.

Conclusions: Similar decreases in weight and indices of adiposity are observed when overweight or obese individuals are fed hypocaloric diets containing levels of sucrose or high fructose corn syrup typically consumed by adults in the United States.

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Figures

Figure 1
Figure 1
Changes in body mass and measures of adiposity after 12 weeks on a (500Kcal/day) hypercaloric diet containing either 10% or 20% of calories from HFCS.
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