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Review
. 2012 Oct;12(5):623-8.
doi: 10.1016/j.coph.2012.07.011. Epub 2012 Jul 31.

Systems biology: personalized medicine for the future?

Rui Chen  1 , Michael Snyder
Affiliations
Review

Systems biology: personalized medicine for the future?

Rui Chen et al. Curr Opin Pharmacol. 2012 Oct.

Abstract

Systems biology is actively transforming the field of modern health care from symptom-based disease diagnosis and treatment to precision medicine in which patients are treated based on their individual characteristics. Development of high-throughput technologies such as high-throughout sequencing and mass spectrometry has enabled scientists and clinicians to examine genomes, transcriptomes, proteomes, metabolomes, and other omics information in unprecedented detail. The combined 'omics' information leads to a global profiling of health and disease, and provides new approaches for personalized health monitoring and preventative medicine. In this article, we review the efforts of systems biology in personalized medicine in the past 2 years, and discuss in detail achievements and concerns, as well as highlights and hurdles for future personalized health care.

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Figures

Figure 1
Figure 1
Integrative Personal Omics Profile (iPOP) Analysis. Various types of systems data can be generated and integrated with the iPOP analysis. Note that this approach is highly modular and can be tailored to meet specific needs of different studies.
See this image and copyright information in PMC

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