Cytoreductive surgery plus hyperthermic perioperative chemotherapy to treat peritoneal metastases from colorectal cancer: standard of care or an experimental approach?
- PMID: 22846841
- DOI: 10.1016/S1470-2045(12)70210-3
Cytoreductive surgery plus hyperthermic perioperative chemotherapy to treat peritoneal metastases from colorectal cancer: standard of care or an experimental approach?
Abstract
Peritoneal carcinomatosis is a common presentation in patients with metastatic colorectal cancer and the overall survival is poor. In most patients, the disease remains limited to the peritoneal cavity. Therefore, investigators have applied cytoreductive surgery and hyperthermic perioperative chemotherapy as the standard approach for selected patients with peritoneal metastases from colorectal cancer. Overall, very promising long-term survival has been shown in a subset of patients with a limited extent of peritoneal disease before treatment. Whether randomised, controlled trials are needed to definitively show the magnitude of benefit, if any, of this approach is an important question. This Debate outlines the arguments on each side of this issue.
Copyright © 2012 Elsevier Ltd. All rights reserved.
Similar articles
-
Peritoneal metastases from colorectal cancer: patient selection for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.Eur J Surg Oncol. 2013 Sep;39(9):931-7. doi: 10.1016/j.ejso.2013.06.001. Epub 2013 Jun 27. Eur J Surg Oncol. 2013. PMID: 23810280 Review.
-
Postoperative complications after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy affect long-term outcome of patients with peritoneal metastases from colorectal cancer: a two-center study of 101 patients.Dis Colon Rectum. 2014 Jul;57(7):858-68. doi: 10.1097/DCR.0000000000000149. Dis Colon Rectum. 2014. PMID: 24901687
-
Treatment of peritoneal carcinomatosis from colorectal cancer by cytoreductive surgery and hyperthermic perioperative intraperitoneal chemotherapy.Eur J Surg Oncol. 2005 Mar;31(2):147-52. doi: 10.1016/j.ejso.2004.09.021. Eur J Surg Oncol. 2005. PMID: 15698730
-
Colorectal peritoneal metastases: Optimal management review.World J Gastroenterol. 2019 Jul 21;25(27):3484-3502. doi: 10.3748/wjg.v25.i27.3484. World J Gastroenterol. 2019. PMID: 31367152 Free PMC article. Review.
-
Patterns of recurrence following complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis of colorectal cancer.J Surg Oncol. 2014 Jun;109(8):841-7. doi: 10.1002/jso.23597. Epub 2014 Mar 12. J Surg Oncol. 2014. PMID: 24619813
Cited by
-
Regional hyperthermia of the abdomen, a pilot study towards the treatment of peritoneal carcinomatosis.Radiat Oncol. 2015 Jul 30;10:157. doi: 10.1186/s13014-015-0451-3. Radiat Oncol. 2015. PMID: 26223271 Free PMC article. Clinical Trial.
-
Peritoneal recurrence after resection for Stage I-III colorectal cancer: A population analysis.J Surg Oncol. 2023 Mar;127(4):678-687. doi: 10.1002/jso.27175. Epub 2022 Dec 15. J Surg Oncol. 2023. PMID: 36519668 Free PMC article.
-
Controversy and consensus on the management of patients with pseudomyxoma peritonei.Curr Treat Options Oncol. 2013 Sep;14(3):365-73. doi: 10.1007/s11864-013-0240-x. Curr Treat Options Oncol. 2013. PMID: 23934509
-
Molecular fluorescence-guided surgery of peritoneal carcinomatosis of colorectal origin: A narrative review.J Surg Oncol. 2018 Aug;118(2):332-343. doi: 10.1002/jso.25106. Epub 2018 Jun 24. J Surg Oncol. 2018. PMID: 29938400 Free PMC article. Review.
-
Colorectal cancer: from prevention to personalized medicine.World J Gastroenterol. 2014 Jun 14;20(22):6786-808. doi: 10.3748/wjg.v20.i22.6786. World J Gastroenterol. 2014. PMID: 24944469 Free PMC article. Review.
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
