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Review
. 2012 Sep;11(5):395-404.
doi: 10.1093/bfgp/els031. Epub 2012 Jul 26.

Genome-wide approaches to understanding behaviour in Drosophila melanogaster

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Review

Genome-wide approaches to understanding behaviour in Drosophila melanogaster

Megan Neville et al. Brief Funct Genomics. 2012 Sep.

Abstract

Understanding how an organism exhibits specific behaviours remains a major and important biological question. Studying behaviour in a simple model organism like the fruit fly Drosophila melanogaster has the advantages of advanced molecular genetics approaches along with well-defined anatomy and physiology. With advancements in functional genomic technologies, researchers are now attempting to uncover genes and pathways involved in complex behaviours on a genome-wide scale. A systems-level network approach, which will include genomic approaches, to study behaviour will be key to understanding the regulation and modulation of behaviours and the importance of context in regulating them.

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