Review
doi: 10.1146/annurev-bioeng-071811-150122.
Tendon healing: repair and regeneration
Affiliations
- PMID: 22809137
- DOI: 10.1146/annurev-bioeng-071811-150122
Item in Clipboard
Review
Tendon healing: repair and regeneration
Annu Rev Biomed Eng.
2012.
Abstract
Injury and degeneration of tendon, the soft tissue that mechanically links muscle and bone, can cause substantial pain and loss of function. This review discusses the composition and function of healthy tendon and describes the structural, biological, and mechanical changes initiated during the process of tendon healing. Biochemical pathways activated during repair, experimental injury models, and parallels between tendon healing and tendon development are emphasized, and cutting-edge strategies for the enhancement of tendon healing are discussed.
Similar articles
-
Therapeutic strategies for tendon healing based on novel biomaterials, factors and cells.Pathobiology. 2013;80(4):203-10. doi: 10.1159/000347059. Epub 2013 May 6. Pathobiology. 2013. PMID: 23652284 Review.
-
Effects of platelet-rich plasma on the quality of repair of mechanically induced core lesions in equine superficial digital flexor tendons: A placebo-controlled experimental study.J Orthop Res. 2010 Feb;28(2):211-7. doi: 10.1002/jor.20980. J Orthop Res. 2010. PMID: 19714688 Clinical Trial.
-
Alendronate prevents bone loss and improves tendon-to-bone repair strength in a canine model.J Orthop Res. 2007 Apr;25(4):473-9. doi: 10.1002/jor.20293. J Orthop Res. 2007. PMID: 17205555
-
An experimental study on the effect of safflower yellow on tendon injury-repair in chickens.J Surg Res. 2011 Aug;169(2):e175-84. doi: 10.1016/j.jss.2011.03.079. Epub 2011 Apr 29. J Surg Res. 2011. PMID: 21601885
-
Tendon regeneration and scar formation: The concept of scarless healing.J Orthop Res. 2015 Jun;33(6):823-31. doi: 10.1002/jor.22853. Epub 2015 Apr 27. J Orthop Res. 2015. PMID: 25676657 Free PMC article. Review.
Cited by
-
Battling adhesions: from understanding to prevention.BMC Biomed Eng. 2019 Feb 27;1:5. doi: 10.1186/s42490-019-0005-0. eCollection 2019. BMC Biomed Eng. 2019. PMID: 32903353 Free PMC article. Review.
-
Bletilla striata Polysaccharide-Containing Carboxymethyl Cellulose Bilayer Structure Membrane for Prevention of Postoperative Adhesion and Achilles Tendon Repair.Biomacromolecules. 2024 Sep 9;25(9):5786-5797. doi: 10.1021/acs.biomac.4c00463. Epub 2024 Jun 27. Biomacromolecules. 2024. PMID: 38935055 Free PMC article.
-
Subcutaneously engineered autologous extracellular matrix scaffolds with aligned microchannels for enhanced tendon regeneration: Aligned microchannel scaffolds for tendon repair.Biomaterials. 2019 Dec;224:119488. doi: 10.1016/j.biomaterials.2019.119488. Epub 2019 Sep 12. Biomaterials. 2019. PMID: 31562997 Free PMC article.
-
A Combination of Oxo-M and 4-PPBP as a potential regenerative therapeutics for tendon injury.Theranostics. 2019 May 31;9(14):4241-4254. doi: 10.7150/thno.35285. eCollection 2019. Theranostics. 2019. PMID: 31281545 Free PMC article.
-
Exercise therapy for tendinopathy: a mixed-methods evidence synthesis exploring feasibility, acceptability and effectiveness.Health Technol Assess. 2023 Oct;27(24):1-389. doi: 10.3310/TFWS2748. Health Technol Assess. 2023. PMID: 37929629 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
