Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2012 Mar;96(2):203-21.
doi: 10.1016/j.mcna.2012.01.005. Epub 2012 Feb 14.

Hypothyroidism: etiology, diagnosis, and management

Jaime P Almandoz  1 , Hossein Gharib
Affiliations
Review

Hypothyroidism: etiology, diagnosis, and management

Jaime P Almandoz et al. Med Clin North Am. 2012 Mar.

Abstract

Hypothyroidism is the result of inadequate production of thyroid hormone or inadequate action of thyroid hormone in target tissues. Primary hypothyroidism is the principal manifestation of hypothyroidism, but other causes include central deficiency of thyrotropin-releasing hormone or thyroid-stimulating hormone (TSH), or consumptive hypothyroidism from excessive inactivation of thyroid hormone. Subclinical hypothyroidism is present when there is elevated TSH but a normal free thyroxine level. Treatment involves oral administration of exogenous synthetic thyroid hormone. This review presents an update on the etiology and types of hypothyroidism, including subclinical disease; drugs and thyroid function; and diagnosis and treatment of hypothyroidism.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles