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Randomized Controlled Trial
. 2012 Jun;14(6):725-8.
doi: 10.1093/icvts/ivs009. Epub 2012 Mar 5.

The effect of neoadjuvant chemoradiotherapy on airway colonization and postoperative respiratory complications in patients undergoing oesophagectomy for oesophageal cancer

Reza Bagheri  1 , Mohammad Taghi RajabiMashhadi, Kiyarash Ghazvini, Amir Asnaashari, Ali Zahediyan, Mehdi Abasi Sahebi
Affiliations
Randomized Controlled Trial

The effect of neoadjuvant chemoradiotherapy on airway colonization and postoperative respiratory complications in patients undergoing oesophagectomy for oesophageal cancer

Reza Bagheri et al. Interact Cardiovasc Thorac Surg. 2012 Jun.

Abstract

Respiratory complication is one of the important postoperative complications of oesophageal cancer. The aim of this study was to evaluate whether neoadjuvant chemotherapy before surgery is effective for postoperative respiratory complications. In this study, patients with oesophageal cancer were divided into two group: one with neoadjuvant therapy and the other without neoadjuvant therapy. Before surgery, they all underwent bronchoscopy and bronchoalveolar lavage. We evaluated respiratory complications and the effects of preoperative neoadjuvant therapy. Forty patients (M/F = 23/17 and mean age 61 years) were enrolled in this study. Twenty-two cases had cancer in the middle part and 18 in the lower part of the oesophagus. Significant correlation was observed between the number of positive micro-organism and difficulty in weaning and receiving neoadjuvant therapy. But no significant correlation was found between neoadjuvant therapy and respiratory complications.

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References

    1. Kelsen D. Preoperative chemoradiotherapy for esophageal cancer. J Clin Oncol. 2001;19:283–5. - PubMed
    1. Sun DR. Ten-year follow-up of esophageal cancer treated by radical radiation therapy: Analysis of 869 patients. Int J Radiat Oncol Biol Phys. 1989;16:329–34. - PubMed
    1. Okawa T, Kita M, Tanaka M, Ikeda M. Results of radiotherapy for inoperable locally advanced esophageal cancer. Int J Radiat Oncol Biol Phys. 1989;17:49–54. - PubMed
    1. Brenner B, Ilson DH, Minsky BD. Treatment of localized esophageal cancer. Semin Oncol. 2004;31:554–65. - PubMed
    1. Avendano CE, Flume PA, Silvestri GA, King LB, Reed CE. Pulmonary complications after esophagectomy. Ann Thorac Surg. 2002;73:922–6. - PubMed

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