Editorial: T cell memory, bone marrow, and aging: the good news
- PMID: 22293941
- PMCID: PMC3290429
- DOI: 10.1189/jlb.0811438
Editorial: T cell memory, bone marrow, and aging: the good news
Abstract
Discussion on the accumulating evidence that bone marrow in old age is not simply the place where immune cells are generated but the where certain memory cells selectively return to provide a set of distinct immune functions during old age.
Comment on
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The impact of aging on memory T cell phenotype and function in the human bone marrow.J Leukoc Biol. 2012 Feb;91(2):197-205. doi: 10.1189/jlb.0611299. Epub 2011 Oct 19. J Leukoc Biol. 2012. PMID: 22013229
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References
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- Tokoyoda K., Hauser A. E., Nakayama T., Radbruch A. (2010) Organization of immunological memory by bone marrow stroma. Nat. Rev. Immunol. 10, 193–200 - PubMed
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- Akbar A. N., Soares M. V., Plunkett F. J., Salmon M. (2000) Differential regulation of CD8+ T cell senescence in mice and men. Mech. Ageing Dev. 121, 69–76 - PubMed
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