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Review
. 2011 Nov-Dec;47(6):635-41.

[Histone-like proteins of bacteria (review)]

[Article in Russian]
  • PMID: 22288191
Review

[Histone-like proteins of bacteria (review)]

[Article in Russian]
A M Anuchin et al. Prikl Biokhim Mikrobiol. 2011 Nov-Dec.

Abstract

Four major families of bacterial histone-like proteins (HU, IHF, H-NS, FIS), united on the basis of structural similarity and performing specific structural and regulatory functions in the cell, are discussed. Histone-like proteins perform topological modification of the chromosome (twisting, bending, and folding) and directly regulate the functioning of promoters of individual operons. Histone-like proteins are critical for the regulation of cell metabolism, are involved in the response to environmental changes, and play a key role in the transition to and maintenance of the quiescent state of bacteria.

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