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Editorial
. 2012 Jan;12(1):3.
doi: 10.1111/j.1600-6143.2011.03937.x.

Literature watch implications for transplantation. The anti-infectious role of the IL-17 pathway

Maria-Luisa Alegre, Jonathan S Bromberg
Editorial

Literature watch implications for transplantation. The anti-infectious role of the IL-17 pathway

Maria-Luisa Alegre et al. Am J Transplant. 2012 Jan.
No abstract available

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Figures

Figure 1
Figure 1. Proposed model of how genetic mutations affect the Th17 pathway
The authors have identified a gain-of-function mutation in STAT1 that antagonizes STAT3-mediated Th17 differentiation (1.), a loss-of-function mutation in IL-17F (2.), a mutation in AIRE resulting in neutralizing anti-IL-17 antibodies (3.) and a loss-of-function mutation in the receptor for IL-17A/F (4.) that are all associated with CMC.
See this image and copyright information in PMC

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References

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