Defining functional dyspepsia
- PMID: 22217348
- DOI: 10.4321/s1130-01082011001200006
Defining functional dyspepsia
Abstract
Dyspepsia and functional dyspepsia represent a highly significant public health issue. A good definition of dyspepsia is key for helping us to better approach symptoms, decision making, and therapy indications.During the last few years many attempts were made at establishing a definition of dyspepsia. Results were little successful on most occasions, and clear discrepancies arose on whether symptoms should be associated with digestion, which types of symptoms were to be included, which anatomic location should symptoms have, etc.The Rome III Committee defined dyspepsia as "a symptom or set of symptoms that most physicians consider to originate from the gastroduodenal area", including the following: postprandial heaviness, early satiety, and epigastric pain or burning. Two new entities were defined: a) food-induced dyspeptic symptoms (postprandial distress syndrome); and b) epigastric pain (epigastric pain syndrome). These and other definitions have shown both strengths and weaknesses. At times they have been much too complex, at times much too simple; furthermore, they have commonly erred on the side of being inaccurate and impractical. On the other hand, some (the most recent ones) are difficult to translate into the Spanish language. In a meeting of gastroenterologists with a special interest in digestive functional disorders, the various aspects of dyspepsia definition were discussed and put to the vote, and the following conclusions were arrived at: dyspepsia is defined as a set of symptoms, either related or unrelated to food ingestion, localized on the upper half of the abdomen. They include: a) epigastric discomfort (as a category of severity) or pain; b) postprandial heaviness; and c) early satiety. Associated complaints include: nausea, belching, bloating, and epigastric burn (heartburn). All these must be scored according to severity and frequency. Furthermore, psychological factors may be involved in the origin of functional dyspepsia. On the other hand, it has proven very difficult to establish a clear correlation between symptoms and pathophysiological mechanisms.
Similar articles
-
Pathophysiological Abnormalities in Functional Dyspepsia Subgroups According to the Rome III Criteria.Am J Gastroenterol. 2017 Jan;112(1):132-140. doi: 10.1038/ajg.2016.499. Epub 2016 Dec 13. Am J Gastroenterol. 2017. PMID: 27958284
-
Rome III functional dyspepsia subdivision in PDS and EPS: recognizing postprandial symptoms reduces overlap.Neurogastroenterol Motil. 2015 Aug;27(8):1069-74. doi: 10.1111/nmo.12585. Neurogastroenterol Motil. 2015. PMID: 26220647
-
Functional dyspepsia--symptoms, definitions and validity of the Rome III criteria.Nat Rev Gastroenterol Hepatol. 2013 Mar;10(3):134-41. doi: 10.1038/nrgastro.2013.14. Epub 2013 Feb 12. Nat Rev Gastroenterol Hepatol. 2013. PMID: 23399526 Review.
-
Functional disorders of the stomach.Semin Gastrointest Dis. 1990 Oct;1(1):23-36. Semin Gastrointest Dis. 1990. PMID: 11537400 Review.
-
The Rome III criteria for the diagnosis of functional dyspepsia in secondary care are not superior to previous definitions.Gastroenterology. 2014 Apr;146(4):932-40; quiz e14-5. doi: 10.1053/j.gastro.2014.01.014. Epub 2014 Jan 11. Gastroenterology. 2014. PMID: 24417817
Cited by
-
Imaging of Morphological Background in Selected Functional and Inflammatory Gastrointestinal Diseases in fMRI.Front Psychiatry. 2020 May 20;11:461. doi: 10.3389/fpsyt.2020.00461. eCollection 2020. Front Psychiatry. 2020. PMID: 32508692 Free PMC article.
-
Dyspepsia in the community: value of a community-based mailed survey to identify potential participants for a randomized clinical trial.Scand J Gastroenterol. 2015 Aug;50(8):959-64. doi: 10.3109/00365521.2014.980317. Epub 2015 Mar 11. Scand J Gastroenterol. 2015. PMID: 25761431 Free PMC article. Clinical Trial.
-
Overlap between functional GI disorders and other functional syndromes: what are the underlying mechanisms?Neurogastroenterol Motil. 2012 Oct;24(10):895-913. doi: 10.1111/j.1365-2982.2012.01993.x. Epub 2012 Aug 2. Neurogastroenterol Motil. 2012. PMID: 22863120 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Medical