Zero mortality in more than 300 hepatic resections: validity of preoperative volumetric analysis

doi:10.1007/s00595-011-0108-2

Comparative Study

. 2012 May;42(5):435-40.

doi: 10.1007/s00595-011-0108-2. Epub 2011 Dec 27.

Zero mortality in more than 300 hepatic resections: validity of preoperative volumetric analysis

Shinji Itoh¹, Ken Shirabe, Akinobu Taketomi, Kazutoyo Morita, Norifumi Harimoto, Eiji Tsujita, Keishi Sugimachi, Yo-Ichi Yamashita, Tomonobu Gion, Yoshihiko Maehara

Affiliations

Affiliation

¹ Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. itoshin@surg2.med.kyushu-u.ac.jp

PMID: 22200757
DOI: 10.1007/s00595-011-0108-2

Comparative Study

Zero mortality in more than 300 hepatic resections: validity of preoperative volumetric analysis

Shinji Itoh et al. Surg Today. 2012 May.

. 2012 May;42(5):435-40.

doi: 10.1007/s00595-011-0108-2. Epub 2011 Dec 27.

Authors

Shinji Itoh¹, Ken Shirabe, Akinobu Taketomi, Kazutoyo Morita, Norifumi Harimoto, Eiji Tsujita, Keishi Sugimachi, Yo-Ichi Yamashita, Tomonobu Gion, Yoshihiko Maehara

Affiliation

¹ Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. itoshin@surg2.med.kyushu-u.ac.jp

PMID: 22200757
DOI: 10.1007/s00595-011-0108-2

Abstract

Purpose: We reviewed a series of patients who underwent hepatic resection at our institution, to investigate the risk factors for postoperative complications after hepatic resection of liver tumors and for procurement of living donor liver transplantation (LDLT) grafts.

Methods: Between April 2004 and August 2007, we performed 304 hepatic resections for liver tumors or to procure grafts for LDLT. Preoperative volumetric analysis was done using 3-dimensional computed tomography (3D-CT) prior to major hepatic resection. We compared the clinicopathological factors between patients with and without postoperative complications.

Results: There was no operative mortality. According to the 3D-CT volumetry, the mean error ratio between the actual and the estimated remnant liver volume was 13.4%. Postoperative complications developed in 96 (31.6%) patients. According to logistic regression analysis, histological liver cirrhosis and intraoperative blood loss >850 mL were significant risk factors of postoperative complications after hepatic resection.

Conclusions: Meticulous preoperative evaluation based on volumetric analysis, together with sophisticated surgical techniques, achieved zero mortality and minimized intraoperative blood loss, which was classified as one of the most significant predictors of postoperative complications after major hepatic resection.

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References

1. Ann Surg. 2009 Jan;249(1):124-8 - PubMed
1. Liver Transpl. 2005 Dec;11(12):1556-62 - PubMed
1. Ann Surg. 2004 Feb;239(2):194-201 - PubMed
1. Arch Surg. 2003 Nov;138(11):1198-206; discussion 1206 - PubMed
1. J Am Coll Surg. 2000 Jul;191(1):38-46 - PubMed

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[1] Ann Surg. 2009 Jan;249(1):124-8 - PubMed

[2] Ann Surg. 2009 Jan;249(1):124-8 - PubMed

[3] Liver Transpl. 2005 Dec;11(12):1556-62 - PubMed

[4] Liver Transpl. 2005 Dec;11(12):1556-62 - PubMed

[5] Ann Surg. 2004 Feb;239(2):194-201 - PubMed

[6] Ann Surg. 2004 Feb;239(2):194-201 - PubMed

[7] Arch Surg. 2003 Nov;138(11):1198-206; discussion 1206 - PubMed

[8] Arch Surg. 2003 Nov;138(11):1198-206; discussion 1206 - PubMed

[9] J Am Coll Surg. 2000 Jul;191(1):38-46 - PubMed

[10] J Am Coll Surg. 2000 Jul;191(1):38-46 - PubMed

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Zero mortality in more than 300 hepatic resections: validity of preoperative volumetric analysis

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Zero mortality in more than 300 hepatic resections: validity of preoperative volumetric analysis

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