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Classical Article
. 2012 Feb;41(1):10-3.
doi: 10.1093/ije/dyr184. Epub 2011 Dec 20.

The epigenotype. 1942

Classical Article

The epigenotype. 1942

C H Waddington. Int J Epidemiol. 2012 Feb.

Abstract

The adult characteristics of animals, i.e. their phenotypes, must be studied in order to reach conclusions about the genotypes, i.e. the hereditary constitutions which form the basic subject-matter of genetics. But between genotype and phenotype lies a whole complex of development processes, for which Dr Waddington proposes the name 'epigenotype.' He here describes some of the general characteristics of an epigenotype, with special reference to the fruit-fly Drosophila melanogaster.

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