Pilot study of home self-administration of subcutaneous depo-medroxyprogesterone acetate for contraception
- PMID: 22079602
- DOI: 10.1016/j.contraception.2011.10.002
Pilot study of home self-administration of subcutaneous depo-medroxyprogesterone acetate for contraception
Abstract
Background: Subcutaneous depo-medroxyprogesterone acetate (DMPA-SC) offers the possibility of self-administration.
Study design: This is a pilot study of self-administration of DMPA-SC. Existing users of the intramuscular preparation (DMPA-IM) who wished to self-inject (n=64) were taught self-administration using DMPA-SC. The main outcome was the continuation rate of the method at 12 months compared to a control group of existing users of DMPA-IM (n=64) who continued to attend a clinic to receive the method. Women's satisfaction with the method and the proportion of self-injections given at correct time were also determined.
Results: The 12-month discontinuation rate of the DMPA-SC group (12%) did not differ significantly from that of the DMPA-IM group (22%) (95% confidence intervals of 13%-33% and 6%-23% for DMPA-SC and DMPA-IM, respectively; p=.23). All self-injections were given within the appropriate interval. There was no significant difference in the proportion of women in either group who were satisfied with the method.
Conclusion: Self-administration of DMPA-SC for contraception is feasible and is associated with similar continuation rates and satisfaction to clinician-administered DMPA-IM.
Copyright © 2012 Elsevier Inc. All rights reserved.
Similar articles
-
Self-administration of subcutaneous depot medroxyprogesterone acetate for contraception: feasibility and acceptability.Contraception. 2012 May;85(5):453-7. doi: 10.1016/j.contraception.2011.09.015. Epub 2011 Nov 12. Contraception. 2012. PMID: 22079605 Clinical Trial.
-
Subcutaneous DMPA vs. intramuscular DMPA: a 2-year randomized study of contraceptive efficacy and bone mineral density.Contraception. 2009 Jul;80(1):7-17. doi: 10.1016/j.contraception.2009.02.005. Epub 2009 Mar 27. Contraception. 2009. PMID: 19501210 Clinical Trial.
-
Pharmacist-administered subcutaneous depot medroxyprogesterone acetate: a pilot randomized controlled trial.Contraception. 2010 Aug;82(2):160-7. doi: 10.1016/j.contraception.2010.01.013. Epub 2010 Feb 19. Contraception. 2010. PMID: 20654757 Clinical Trial.
-
Depo Provera. Position paper on clinical use, effectiveness and side effects.Br J Fam Plann. 1999 Jul;25(2):69-76. Br J Fam Plann. 1999. PMID: 10454658 Review.
-
The safety of subcutaneously administered depot medroxyprogesterone acetate (104mg/0.65mL): A systematic review.Contraception. 2016 Sep;94(3):202-15. doi: 10.1016/j.contraception.2016.02.003. Epub 2016 Feb 10. Contraception. 2016. PMID: 26874275 Review.
Cited by
-
A Systematic Review of Patients' Perspectives on the Subcutaneous Route of Medication Administration.Patient. 2016 Aug;9(4):281-92. doi: 10.1007/s40271-015-0160-x. Patient. 2016. PMID: 26792584 Review.
-
Cost-effectiveness of self-injected DMPA-SC compared with health-worker-injected DMPA-IM in Senegal.Contracept X. 2019;1:100012. doi: 10.1016/j.conx.2019.100012. Contracept X. 2019. PMID: 32494776 Free PMC article.
-
Lanreotide extended-release aqueous-gel formulation, injected by patient, partner or healthcare provider in patients with acromegaly in the United States: 1-year data from the SODA registry.Pituitary. 2014 Feb;17(1):13-21. doi: 10.1007/s11102-012-0460-2. Pituitary. 2014. PMID: 23314980 Free PMC article.
-
Self-administration of injectable contraceptives: a systematic review.BJOG. 2017 Jan;124(2):200-208. doi: 10.1111/1471-0528.14248. Epub 2016 Aug 23. BJOG. 2017. PMID: 27550792 Free PMC article. Review.
-
Is a lower-dose, subcutaneous contraceptive injectable containing depot medroxyprogesterone acetate likely to impact women's risk of HIV?Contraception. 2018 Mar;97(3):191-197. doi: 10.1016/j.contraception.2017.12.003. Epub 2017 Dec 11. Contraception. 2018. PMID: 29242082 Free PMC article. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources