[Breast feeding during methadon- and buprenorphin therapy]
- PMID: 21969026
- DOI: 10.1055/s-0031-1283193
[Breast feeding during methadon- and buprenorphin therapy]
Abstract
The number of opiate addicted patients treated with opioid replacement therapy is continuously increasing. In Germany, 57.7% of these patients are treated with methadone and 18.6% with buprenorphine. This maintenance therapy provides several advantages while addicted pregnant women and their foetus have a high benefit from appropriate replacement therapy. However, the recommendations concerning breast feeding during an opioid replacement therapy are discussed controversially, because methadone as well as buprenorphine accumulate in breast milk. This accumulation might cause damages to the newborn's health; so, child benefits of breast feeding have to be balanced with possible health risks.This review provides an overview of a selective literature search based on the PubMed-database and german consensus recommendations. Used search terms included: (methadone*) AND (breastfeeding OR lactation), (methadone*) AND (human milk), (buprenorphine*) AND (breastfeeding OR lactation) and (buprenorphine*) AND (human milk).According to the available literature, addicted women, substinated with methadone or buprenorphine are allowed to breast feed their newborns. The advantages of breast feeding prevail the risks of an infant opiate intoxication caused by methadone or buprenorphine.
© Georg Thieme Verlag KG Stuttgart · New York.
Similar articles
-
Buprenorphine versus methadone in pregnant opioid-dependent women: a prospective multicenter study.Eur J Clin Pharmacol. 2011 Oct;67(10):1053-9. doi: 10.1007/s00228-011-1049-9. Epub 2011 May 3. Eur J Clin Pharmacol. 2011. PMID: 21538146 Clinical Trial.
-
Differences in the profile of neonatal abstinence syndrome signs in methadone- versus buprenorphine-exposed neonates.Addiction. 2012 Nov;107 Suppl 1(0 1):53-62. doi: 10.1111/j.1360-0443.2012.04039.x. Addiction. 2012. PMID: 23106927 Free PMC article. Clinical Trial.
-
Breastfeeding rates and the relationship between breastfeeding and neonatal abstinence syndrome in women maintained on buprenorphine during pregnancy.J Midwifery Womens Health. 2013 Jul-Aug;58(4):383-8. doi: 10.1111/jmwh.12009. J Midwifery Womens Health. 2013. PMID: 23931660
-
Peripartum Anesthetic Management of the Opioid-tolerant or Buprenorphine/Suboxone-dependent Patient.Clin Obstet Gynecol. 2017 Jun;60(2):447-458. doi: 10.1097/GRF.0000000000000288. Clin Obstet Gynecol. 2017. PMID: 28426507 Review.
-
Breastfeeding promotion for management of neonatal abstinence syndrome.J Obstet Gynecol Neonatal Nurs. 2013 Sep-Oct;42(5):517-26. doi: 10.1111/1552-6909.12242. Epub 2013 Sep 4. J Obstet Gynecol Neonatal Nurs. 2013. PMID: 24020477 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical