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. 2011 Aug;33(6):475-9.
doi: 10.1097/MPH.0b013e31820e7361.

Survival outcome of childhood acute lymphoblastic leukemia in India: a resource-limited perspective of more than 40 years

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Survival outcome of childhood acute lymphoblastic leukemia in India: a resource-limited perspective of more than 40 years

Ketan Prasad Kulkarni et al. J Pediatr Hematol Oncol. 2011 Aug.

Abstract

The outcome of childhood acute lymphoblastic leukemia in India has been inferior to more than 80% cure rates in developed nations. This study was done to analyze the outcome of acute lymphoblastic leukemia in India over 4 decades. There has been a gradual improvement in survival rates of up to >70% in some centers along with a decline in relapse and mortality. However, these results cannot be generalized to the entire nation. There is a crying need to address treatment abandonment, take quality improvement, educational and financial initiatives; cooperative research into risk factors and disease biology, and the implementation of risk stratification along with the assessment of response to therapy.

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