Review
doi: 10.1016/j.micinf.2011.06.005.
Epub 2011 Jul 1.
The role of semen in sexual transmission of HIV: beyond a carrier for virus particles
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- PMID: 21767659
- DOI: 10.1016/j.micinf.2011.06.005
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Review
The role of semen in sexual transmission of HIV: beyond a carrier for virus particles
Microbes Infect.
2011 Nov.
Free article
Abstract
Unprotected sexual intercourse between discordant couples is by far the most frequent mode of HIV-1 (human immunodeficiency virus type 1) transmission being semen the main vector for HIV-1 dissemination worldwide. Semen is usually considered merely as a vehicle for HIV-1 transmission. In this review we discuss recent observations suggesting that beyond being a carrier for virus particles semen markedly influences the early events involved in sexual transmission of HIV through the mucosal barriers.
Copyright © 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
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