Review
doi: 10.1152/physiol.00054.2010.
Cell polarity and migration: emerging role for the endosomal sorting machinery
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- PMID: 21670163
- DOI: 10.1152/physiol.00054.2010
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Review
Cell polarity and migration: emerging role for the endosomal sorting machinery
Physiology (Bethesda).
2011 Jun.
Free article
Abstract
The endosomal sorting complex required for transport (ESCRT) machinery has been implicated in the regulation of endosomal sorting, cell division, viral budding, autophagy, and cell signaling. Here, we review recent evidence that implicates ESCRTs in cell polarity and cell migration, and discuss the potential role of ESCRTs as tumor suppressors.
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