Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Mar;64(3):1407-9.
doi: 10.1128/JVI.64.3.1407-1409.1990.

Early death after feline infectious peritonitis virus challenge due to recombinant vaccinia virus immunization

Affiliations

Early death after feline infectious peritonitis virus challenge due to recombinant vaccinia virus immunization

H Vennema et al. J Virol. 1990 Mar.

Abstract

The gene encoding the fusogenic spike protein of the coronavirus causing feline infectious peritonitis was recombined into the genome of vaccinia virus. The recombinant induced spike-protein-specific, in vitro neutralizing antibodies in mice. When kittens were immunized with the recombinant, low titers of neutralizing antibodies were obtained. After challenge with feline infectious peritonitis virus, these animals succumbed earlier than did the control group immunized with wild-type vaccinia virus (early death syndrome).

PubMed Disclaimer

Similar articles

Cited by

References

    1. Am J Vet Res. 1981 Mar;42(3):382-90 - PubMed
    1. Am J Vet Res. 1981 Dec;42(12):2036-48 - PubMed
    1. Comp Immunol Microbiol Infect Dis. 1981;4(2):175-89 - PubMed
    1. Am J Vet Res. 1983 Feb;44(2):229-34 - PubMed
    1. Adv Virus Res. 1986;31:335-55 - PubMed

Publication types

MeSH terms

LinkOut - more resources