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. 1990 Jan;64(1):424-7.
doi: 10.1128/JVI.64.1.424-427.1990.

Human cells infected with retrovirus vectors acquire an endogenous murine provirus

D T Scadden  1 , B Fuller, J M Cunningham
Affiliations

Human cells infected with retrovirus vectors acquire an endogenous murine provirus

D T Scadden et al. J Virol. 1990 Jan.

Abstract

A 5.2-kilobase mouse RNA is expressed in human cells following infection with recombinant retroviruses propagated in mouse NIH 3T3 cells as psi-2 pseudotypes. This RNA is transcribed from a defective mink cell focus-forming provirus and copackaged into virions and integrated into human target cell DNA at a frequency comparable to that of the recombinant retrovirus genome.

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