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Review
. 2011 Aug;32(4):547-50.
doi: 10.1007/s10072-011-0566-8. Epub 2011 Apr 6.

Temporal lobe epilepsy and anti glutamic acid decarboxylase autoimmunity

Luca Errichiello  1 , Salvatore Striano, Federico Zara, Pasquale Striano
Affiliations
Review

Temporal lobe epilepsy and anti glutamic acid decarboxylase autoimmunity

Luca Errichiello et al. Neurol Sci. 2011 Aug.

Abstract

Epilepsy is one of the most impactful diseases on social life. A significant number of epileptic syndromes have been linked to immunological alterations. Elevated levels of antibodies against glutamic acid decarboxylase have been recently found in a significant percentage of patients with temporal lobe epilepsy, the most common epilepsy type. The clinical and pathogenetic relationship of this association is discussed. This link may have important therapeutic implications and merits additional clinical and laboratory research.

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