Comment
doi: 10.1016/j.molcel.2011.03.001.
UPF1 learns to relax and unwind
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- PMID: 21419337
- DOI: 10.1016/j.molcel.2011.03.001
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Comment
UPF1 learns to relax and unwind
Mol Cell.
.
Free article
Abstract
In this issue of Molecular Cell, Chakrabarti et al. (2011) structurally reveal how UPF1, an RNA helicase that plays a central role in nonsense-mediated mRNA decay, is conformationally converted from a largely inactive state to an active state upon UPF2 binding.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2.Mol Cell. 2011 Mar 18;41(6):693-703. doi: 10.1016/j.molcel.2011.02.010. Mol Cell. 2011. PMID: 21419344
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