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. 2010 Dec;6(12):866-8.
doi: 10.1038/nchembio.471.

Grand challenge commentary: The chemistry of a dynamic genome

Rahul M Kohli  1
Affiliations

Grand challenge commentary: The chemistry of a dynamic genome

Rahul M Kohli. Nat Chem Biol. 2010 Dec.

Abstract

In the postsequencing era, chemical biology is uniquely situated to investigate genomic DNA alterations arising through epigenetic modifications, genetic rearrangements or active mutation. These transformations significantly expand nature's diversity and may profoundly alter our view of DNA's coding potential.

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