Comment
doi: 10.1038/ng0910-731.
Infectious diseases not immune to genome-wide association
- PMID: 20802473
- DOI: 10.1038/ng0910-731
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Comment
Infectious diseases not immune to genome-wide association
Nat Genet.
2010 Sep.
Abstract
Two genome-wide association studies for meningococcal disease and tuberculosis identify new loci associated with susceptibility to these infectious diseases. They highlight a role for the acquired and innate immune systems in host control of several human pathogens and demonstrate that denser genotyping platforms and population-specific reference panels are necessary for genetic studies in African populations.
Comment on
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Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease.Nat Genet. 2010 Sep;42(9):772-6. doi: 10.1038/ng.640. Epub 2010 Aug 8. Nat Genet. 2010. PMID: 20694013
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Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.Nat Genet. 2010 Sep;42(9):739-741. doi: 10.1038/ng.639. Epub 2010 Aug 8. Nat Genet. 2010. PMID: 20694014 Free PMC article.
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