Review
doi: 10.1016/j.cld.2010.05.007.
Natural history of chronic hepatitis B
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- PMID: 20638020
- DOI: 10.1016/j.cld.2010.05.007
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Review
Natural history of chronic hepatitis B
Clin Liver Dis.
2010 Aug.
Abstract
In this article, the 4 phases of chronic HBV infection are reviewed and the factors that are associated with disease progression and the development of hepatocellular carcinoma (HCC) and cirrhosis are discussed. Also discussed is what is known to date about how to identify persons at the highest risk of developing HCC and/or cirrhosis. Finally, ways in which the natural history can be altered by hepatitis B vaccination and identification, close monitoring, and appropriate treatment of chronically infected individuals are reviewed.
2010 Elsevier Inc. All rights reserved.
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