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Review
. 2010 May;130(5):713-5.
doi: 10.1248/yakushi.130.713.

[Clinical research on improvement of glucose metabolic marker level by coffee drinking-validity of saliva caffeine concentration measurement]

[Article in Japanese]
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Free article
Review

[Clinical research on improvement of glucose metabolic marker level by coffee drinking-validity of saliva caffeine concentration measurement]

[Article in Japanese]
Tomoko Okada et al. Yakugaku Zasshi. 2010 May.
Free article

Abstract

We measured both serum and saliva caffeine concentration using HPLC and assessed the correlation between them in volunteers with mild obesity. Significant correlation was shown between saliva and serum caffeine concentration. It may be necessary to measure caffeine metabolite concentration because its metabolites may also have an improving effect of glucose metabolism. In summary, we found that saliva caffeine concentration measurement was useful to assess caffeine intake level. Moreover, it will be helpful to know whether caffeine has an improving effect of glucose metabolism.

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