doi: 10.1021/np900724u.
Antimicrobial triterpenoid glycosides from Cephalaria scoparia
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- PMID: 20384364
- DOI: 10.1021/np900724u
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Antimicrobial triterpenoid glycosides from Cephalaria scoparia
J Nat Prod.
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Abstract
Five new oleanane-type triterpenoid glycosides (1-5), named scoposides A-E, along with one known bisdesmosidic triterpene glycoside, were isolated from the aerial parts of Cephalaria scoparia. Three prosapogenins (2a-4a) were also obtained after alkaline hydrolysis of the bisdesmosidic compounds 2-4. The structures of compounds 1-5 were determined by spectroscopic (1D and 2D NMR, HRESIMS) and chemical methods. The antimicrobial effects of compounds 1-5 were evaluated against a small panel of Gram-positive and Gram-negative bacteria.
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