[Depression in Parkinson's disease]
- PMID: 19856889
[Depression in Parkinson's disease]
Abstract
Parkinson's disease (PD) belongs to degenerative diseases of brain in which, apart from many somatic symptoms, there also occur depressive disorders of mental sphere. This paper presents possible reasons for the development of depression in PD: psychological resulting from the presence and the development of chronic disease as well as neurochemical disorders that reveal in this background. It has been highlighted that the presence of PD has a significant effect on the patients' life quality The paper discusses possible important factors for the progress of depression syndromes: decrease in everyday life activities, somatic state heaviness, worsening of motor functions, cognitive deficits. The possible occurrence of typical depression syndrome manifested in PD, its modifications and possible axial symptoms were analyzed. Two modifications of depression syndrome were also described. The results of the study on the increased lethality in patients with PD were presented. Special attention was paid to the occurrence of apathy with no key signs of depression syndrome. The existence of relations linking the apathy with cognitive disorders were highlighted. The paper discusses the occurrence of factors that may affect the revealing of apathy, as well as the presence of possible brain dysfunctions in patients.
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