Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2009 Oct;197(10):715-21.
doi: 10.1097/NMD.0b013e3181b97d4d.

Predictors of clinical improvement in a randomized effectiveness trial for primary care patients with panic disorder

Denise A Chavira  1 , Murray B Stein, Daniela Golinelli, Cathy D Sherbourne, Michelle G Craske, Greer Sullivan, Alexander Bystritsky, Peter P Roy-Byrne
Affiliations
Randomized Controlled Trial

Predictors of clinical improvement in a randomized effectiveness trial for primary care patients with panic disorder

Denise A Chavira et al. J Nerv Ment Dis. 2009 Oct.

Abstract

This study's aim was to prospectively examine and identify a model of demographic, clinical, and attitudinal variables that impact improvement among patients with panic disorder. Subjects were 232 primary care patients meeting criteria for DSM-IV panic disorder. Eligible patients were randomly assigned to a collaborative care intervention or to treatment as usual. Assessments occurred at 3-month intervals during the course of 1 year. In final multivariate logistic regression models, patients with higher anxiety sensitivity and higher neuroticism scores at baseline were less likely to show clinical improvement (using a criterion of 20 or less on the Anxiety Sensitivity Index) at 3 months. Those who were non-white, had higher anxiety sensitivity, and higher overall phobic avoidance at baseline were less likely to show clinical improvement at 12 months. A greater understanding of these predictors may help clinicians identify who is at greatest risk for persistent panic-related symptoms and to plan the intensity of interventions accordingly.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Akaike H. A new Look at statistical model identification. IEEE Transactions on Automatic Control. 1974;19:716–722.
    1. Alvidrez J. Ethnic variations in mental health attitudes and service use among low-income African American, Latina, and European American young women. Community Ment Health J. 1999;35:515–530. - PubMed
    1. Alvidrez J, Azocar F. Distressed women's clinic patients: preferences for mental health treatments and perceived obstacles. Gen Hosp Psychiatry. 1999;21:340–347. - PubMed
    1. Barron F, Hunter A, Mayo R, Willoughby D. Acculturation and adherence: Issues for health care providers working with clients of Mexican origin. J Transcult Nursing. 2004;15:331–337. - PubMed
    1. Berger P, Sachs G, Amering M, Holzinger A, Bankier B, Katschnig H. Personality disorder and social anxiety predict delayed response in drug and behavioral treatment of panic disorder. J Affect Disord. 2004;80:75–78. - PubMed

Publication types

MeSH terms

Substances