doi: 10.1002/jmr.978.
Base pairs and pseudo pairs observed in RNA-ligand complexes
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- PMID: 19701919
- DOI: 10.1002/jmr.978
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Base pairs and pseudo pairs observed in RNA-ligand complexes
J Mol Recognit.
2010 Mar-Apr.
Abstract
Previously, a geometric nomenclature was proposed in which RNA base pairs were classified by their interaction edges (Watson-Crick, Hoogsteen or sugar-edge) and the glycosidic bond orientations relative to the hydrogen bonds formed (cis or trans). Here, base pairs and pseudo pairs observed in RNA-ligand complexes are classified in a similar manner. Twenty-one basic geometric families are geometrically possible (18 for base pairs formed between a nucleic acid base and a ligand containing heterocycle and 3 families for pseudo pairs). Of those, 16 of them have been observed in X-ray and/or NMR structures.
2009 John Wiley & Sons, Ltd.
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