Review
doi: 10.1002/jcp.21895.
Cell based therapy for Duchenne muscular dystrophy
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- PMID: 19688776
- DOI: 10.1002/jcp.21895
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Review
Cell based therapy for Duchenne muscular dystrophy
J Cell Physiol.
2009 Dec.
Abstract
Mutations in the dystrophin gene cause an X-linked genetic disorder: Duchenne muscular dystrophy (DMD). Stem cell therapy is an attractive method to treat DMD because a small number of cells are required to obtain a therapeutic effect. Here, we discussed about multiple types of myogenic stem cells and their possible use to treat DMD. The identification of a stem cell population providing efficient muscle regeneration is critical for the progression of cell therapy for DMD. We speculated that the most promising possibility for the treatment of DMD is a combination of different approaches, such as gene and stem cell therapy.
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