Post-inflammatory retinal dystrophy in CINCA syndrome

doi:10.1007/s00296-009-0939-y

Case Reports

. 2010 Jan;30(3):389-93.

doi: 10.1007/s00296-009-0939-y. Epub 2009 May 8.

Post-inflammatory retinal dystrophy in CINCA syndrome

Donato Rigante¹, Achille Stabile, Angelo Minnella, Laura Avallone, Lucia Ziccardi, Giulia Bersani, Giovanna Stifano, Adele Compagnone, Benedetto Falsini

Affiliations

Affiliation

¹ Department of Pediatric Sciences, Center of Periodic Fevers, Università Cattolica Sacro Cuore, Largo A. Gemelli no. 8, 00168 Rome, Italy. drigante@gmail.com

PMID: 19424698
DOI: 10.1007/s00296-009-0939-y

Case Reports

Post-inflammatory retinal dystrophy in CINCA syndrome

Donato Rigante et al. Rheumatol Int. 2010 Jan.

. 2010 Jan;30(3):389-93.

doi: 10.1007/s00296-009-0939-y. Epub 2009 May 8.

Authors

Donato Rigante¹, Achille Stabile, Angelo Minnella, Laura Avallone, Lucia Ziccardi, Giulia Bersani, Giovanna Stifano, Adele Compagnone, Benedetto Falsini

Affiliation

¹ Department of Pediatric Sciences, Center of Periodic Fevers, Università Cattolica Sacro Cuore, Largo A. Gemelli no. 8, 00168 Rome, Italy. drigante@gmail.com

PMID: 19424698
DOI: 10.1007/s00296-009-0939-y

Abstract

Right chorioretinitis and bilateral pseudopapilledema were firstly appreciated in a 9-month-old child with neonatal findings of aseptic chronic meningitis, framed in the context of CINCA syndrome at 1 year. Therapeutical response to various combinations of drugs was inconsistent until 7 years, when anakinra was started with immediate clinical and laboratory improvement. A state of severe retinal dystrophy of post-inflammatory origin became evident on funduscopy, optical coherence tomography and visual electrophysiology tests at the age of 10 years, which remained stationary after 1 year of anakinra treatment.

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Gaggiano C, Rigante D, Vitale A, Lucherini OM, Fabbiani A, Capozio G, Marzo C, Gelardi V, Grosso S, Frediani B, Renieri A, Cantarini L. Gaggiano C, et al. Mediators Inflamm. 2019 Dec 31;2019:3293145. doi: 10.1155/2019/3293145. eCollection 2019. Mediators Inflamm. 2019. PMID: 32082075 Free PMC article. Review.
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References

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[1] J Pediatr. 1997 Apr;130(4):513-5 - PubMed

[2] J Pediatr. 1997 Apr;130(4):513-5 - PubMed

[3] Acta Paediatr. 2001 Sep;90(9):1076-9 - PubMed

[4] Acta Paediatr. 2001 Sep;90(9):1076-9 - PubMed

[5] Graefes Arch Clin Exp Ophthalmol. 2008 Aug;246(8):1153-62 - PubMed

[6] Graefes Arch Clin Exp Ophthalmol. 2008 Aug;246(8):1153-62 - PubMed

[7] Eur Rev Med Pharmacol Sci. 2006 Sep-Oct;10(5):229-34 - PubMed

[8] Eur Rev Med Pharmacol Sci. 2006 Sep-Oct;10(5):229-34 - PubMed

[9] N Engl J Med. 2001 May 3;344(18):1366-71 - PubMed

[10] N Engl J Med. 2001 May 3;344(18):1366-71 - PubMed

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Post-inflammatory retinal dystrophy in CINCA syndrome

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