Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Aug;40(1):46-54.
doi: 10.1007/s12035-009-8068-x. Epub 2009 Apr 29.

Regulation of dendrite and spine morphogenesis and plasticity by catenins

Jyothi Arikkath  1
Affiliations
Review

Regulation of dendrite and spine morphogenesis and plasticity by catenins

Jyothi Arikkath. Mol Neurobiol. 2009 Aug.

Abstract

The appropriate regulation of dendrite, spine, and synapse morphogenesis in neurons both during and after development is critical for the formation and maintenance of neural circuits. It is becomingly increasingly clear that the cadherin-catenin cell adhesion complex, a complex that has been widely studied in epithelia, regulates neuronal morphogenesis. More interestingly, the catenins, cytosolic proteins that bind to cadherins, regulate multiple aspects of neuronal morphogenesis including dendrite, spine, and synapse morphogenesis and plasticity, both independent of and dependent on their ability to bind cadherins. In this review, we examine some of the more recent and exciting studies that implicate individual catenins in various aspects of neuronal morphogenesis and plasticity.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Cell Biol. 2002 Nov 11;159(3):465-76 - PubMed
    1. Annu Rev Cell Dev Biol. 2008;24:183-209 - PubMed
    1. Neuron. 2006 Jul 6;51(1):43-56 - PubMed
    1. Genomics. 2000 Jan 15;63(2):157-64 - PubMed
    1. Neuron. 2002 Jul 3;35(1):91-105 - PubMed

Publication types

LinkOut - more resources